PPI H2 blocker combination延伸文章資訊，搜尋引擎最佳文章推薦
1. H2 Blockers: Treatment Options for GERD
Doctors usually don't recommend taking both a PPI and an H2 receptor blocker at the same time. H2 receptor blockers can interfere with the effectiveness of PPIs.H2ReceptorBlockersMedicallyreviewedbyTylerWalker,MD—WrittenbyMichaelKerr—UpdatedonApril9,2020OverviewProcessSideEffectsH2ReceptorBlockersvs.ProtonPumpInhibitors(PPIs)AlternativesWITHDRAWALOFRANITIDINEInApril2020,theFoodandDrugAdministration(FDA)requestedthatallformsofprescriptionandover-the-counter(OTC)ranitidine(Zantac)beremovedfromtheU.S.market.ThisrecommendationwasmadebecauseunacceptablelevelsofNDMA,aprobablecarcinogen(cancer-causingchemical),werefoundinsomeranitidineproducts.Ifyou’represcribedranitidine,talkwithyourdoctoraboutsafealternativeoptionsbeforestoppingthedrug.Ifyou’retakingOTCranitidine,stoptakingthedrugandtalkwithyourhealthcareprovideraboutalternativeoptions.Insteadoftakingunusedranitidineproductstoadrugtake-backsite,disposeofthemaccordingtotheproduct’sinstructionsorbyfollowingtheFDA’sguidance.WhatAreH2ReceptorBlockers?H2receptorblockersareaclassofmedicationsthatcanbeusedtotreatconditionsthatcauseexcessstomachacid.Thesemedicationsareavailableoverthecounterandbyprescription.CommonH2receptorblockersinclude:nizatidine(Axid)famotidine(Pepcid,PepcidAC)cimetidine(Tagamet,TagametHB)H2receptorblockersaremostcommonlyusedtotreatgastritis,orinflamedstomach,andtotreatpepticulcers.Pepticulcersarepainfulsoresthatformintheliningofthestomach,loweresophagus,orduodenum,whichisthefirstpartofthesmallintestine.Theyoftendevelopasaresultofinflammationandexcessstomachacid.DoctorsmayalsorecommendH2receptorblockerstokeeppepticulcersfromreturning.H2receptorblockersarealsofrequentlyusedtorelievethesymptomsofgastroesophagealrefluxdisease(GERD).GERDisachronicformofacidreflux,whichcausesacidicstomachcontentstoflowbackupintotheesophagus.Thefrequentexposuretostomachacidcanirritatetheesophagusandleadtouncomfortablesymptoms,suchasheartburn,nausea,ortroubleswallowing.H2blockersmayalsobeusedtotreatlesscommonconditionssuchasZollin
2. Administration of H2 Receptor Antagonist With Proton Pump In ...
1 The additional administration of H2 receptor antagonist (H2RA) at bedtime ... may occur for a relatively short period by combination therapy for H2RA and PPI.March2004-Volume38-Issue3PreviousAbstractNextAbstractFullTextAccessforSubscribers:IndividualSubscribersLoginforaccessInstitutionalMembersAccessonOvid®NotaSubscriber?BuySubscribeRequestPermissionsYoucanreadthefulltextofthisarticleifyou:SelectanoptionLogInBuyArticleSubscribeContent&PermissionsOvidMemberInstitutionalAccessLogInOvidMemberInstitutionalAccessArticleasEPUBExportAllImagestoPowerPointFileAddtoMyFavoritesColleague'sE-mailisInvalidYourName:(optional)YourEmail:Colleague'sEmail:Separatemultiplee-mailswitha(;).Message:Thoughtyoumightappreciatethisitem(s)IsawatJournalofClinicalGastroenterology.SendacopytoyouremailYourmessagehasbeensuccessfullysenttoyourcolleague.Someerrorhasoccurredwhileprocessingyourrequest.Pleasetryaftersometime.EndNoteProciteReferenceManagerSavemyselectionLetterstotheEditorAdachi,KyoichiMD;Komazawa,YoshinoriMD;Mihara,TakafumiMD;Fujishiro,HirofumiMD;Ishihara,ShunjiMD;Amano,YujiMD;Kinoshita,YoshikazuMDAuthorInformationShimaneUniversityIzumo,JapanJournalofClinicalGastroenterology:March2004-Volume38-Issue3-p297-298Buy©2004LippincottWilliams&Wilkins,Inc.SourceAdministrationofH2ReceptorAntagonistWithProtonPumpInhibitorIsEffectiveforLong-termControlofRefractoryRefluxEsophagitisJournalofClinicalGastroenterology38(3):297-298,March2004.Full-SizeEmail+FavoritesExportViewinGalleryColleague'sE-mailisInvalidYourName:(optional)YourEmail:Colleague'sEmail:Separatemultiplee-mailswitha(;).Message:Thoughtyoumightappreciatethisitem(s)IsawatJournalofClinicalGastroenterology.SendacopytoyouremailYourmessagehasbeensuccessfullysenttoyourcolleague.Someerrorhasoccurredwhileprocessingyourrequest.Pleasetryaftersometime.AddItem(s)to: AnExistingFolderANewFolderFolderName:Description:Theitem(s)hasbeensuccessfullyaddedto"".Thanksforregistering!Besuretoverifyyournewuseraccountinthenext24hours,bycheckingyouremailandclickin
3. Addition of a H2 receptor antagonist to PPI improves acid ...
Abstract · Background: The addition of a bedtime H2 receptor antagonist (H2RA) to proton pump inhibitor (PPI) b.i.d. to inhibit nocturnal acid breakthrough (NAB) is ...Clipboard,SearchHistory,andseveralotheradvancedfeaturesaretemporarilyunavailable.SkiptomainpagecontentCOVID-19InformationPublichealthinformation(CDC)Researchinformation(NIH)SARS-CoV-2data(NCBI)Preventionandtreatmentinformation(HHS)Español AccesskeysNCBIHomepageMyNCBIHomepageMainContentMainNavigationSearch:SearchAdvancedClipboardUserGuideSaveEmailSendtoClipboardMyBibliographyCollectionsCitationmanagerDisplayoptionsDisplayoptionsFormatAbstractPubMedPMIDSavecitationtofileFormat:Summary(text)PubMedPMIDAbstract(text)CSVCreatefileCancelEmailcitationSubject:1selecteditem:18496394-PubMedTo:Format:SummarySummary(text)AbstractAbstract(text)MeSHandotherdataSendemailCancelAddtoCollectionsCreateanewcollectionAddtoanexistingcollectionNameyourcollection:Namemustbelessthan100charactersChooseacollection:UnabletoloadyourcollectionduetoanerrorPleasetryagainAddCancelAddtoMyBibliographyMyBibliographyUnabletoloadyourdelegatesduetoanerrorPleasetryagainAddCancelYoursavedsearchNameofsavedsearch:Searchterms:TestsearchtermsWouldyoulikeemailupdatesofnewsearchresults?SavedSearchAlertRadioButtonsYesNoEmail:(change)Frequency:MonthlyWeeklyDailyWhichday?ThefirstSundayThefirstMondayThefirstTuesdayThefirstWednesdayThefirstThursdayThefirstFridayThefirstSaturdayThefirstdayThefirstweekdayWhichday?SundayMondayTuesdayWednesdayThursdayFridaySaturdayReportformat:SummarySummary(text)AbstractAbstract(text)PubMedSendatmost:1item5items10items20items50items100items200itemsSendevenwhentherearen'tanynewresultsOptionaltextinemail:SaveCancelCreateafileforexternalcitationmanagementsoftwareCreatefileCancelYourRSSFeedNameofRSSFeed:Numberofitemsdisplayed:510152050100CreateRSSCancelRSSLinkCopyFulltextlinksWoltersKluwerFulltextlinksActionsCiteFavoritesDisplayoptionsDisplayoptionsFormatAbstractPubMedPMIDSharePermalinkCopyPagenavigationTitle&authorsAbstractSi
4. Combination drug therapy for gastroesophageal reflux disease
No studies in patients with GERD demonstrate that the addition of histamine(2) receptor antagonists to twice-daily PPI therapy provides any further benefit above ...Clipboard,SearchHistory,andseveralotheradvancedfeaturesaretemporarilyunavailable.SkiptomainpagecontentCOVID-19InformationPublichealthinformation(CDC)Researchinformation(NIH)SARS-CoV-2data(NCBI)Preventionandtreatmentinformation(HHS)Español AccesskeysNCBIHomepageMyNCBIHomepageMainContentMainNavigationSearch:SearchAdvancedClipboardUserGuideSaveEmailSendtoClipboardMyBibliographyCollectionsCitationmanagerDisplayoptionsDisplayoptionsFormatAbstractPubMedPMIDSavecitationtofileFormat:Summary(text)PubMedPMIDAbstract(text)CSVCreatefileCancelEmailcitationSubject:1selecteditem:11978171-PubMedTo:Format:SummarySummary(text)AbstractAbstract(text)MeSHandotherdataSendemailCancelAddtoCollectionsCreateanewcollectionAddtoanexistingcollectionNameyourcollection:Namemustbelessthan100charactersChooseacollection:UnabletoloadyourcollectionduetoanerrorPleasetryagainAddCancelAddtoMyBibliographyMyBibliographyUnabletoloadyourdelegatesduetoanerrorPleasetryagainAddCancelYoursavedsearchNameofsavedsearch:Searchterms:TestsearchtermsWouldyoulikeemailupdatesofnewsearchresults?SavedSearchAlertRadioButtonsYesNoEmail:(change)Frequency:MonthlyWeeklyDailyWhichday?ThefirstSundayThefirstMondayThefirstTuesdayThefirstWednesdayThefirstThursdayThefirstFridayThefirstSaturdayThefirstdayThefirstweekdayWhichday?SundayMondayTuesdayWednesdayThursdayFridaySaturdayReportformat:SummarySummary(text)AbstractAbstract(text)PubMedSendatmost:1item5items10items20items50items100items200itemsSendevenwhentherearen'tanynewresultsOptionaltextinemail:SaveCancelCreateafileforexternalcitationmanagementsoftwareCreatefileCancelYourRSSFeedNameofRSSFeed:Numberofitemsdisplayed:510152050100CreateRSSCancelRSSLinkCopyFulltextlinksAtyponFulltextlinksActionsCiteFavoritesDisplayoptionsDisplayoptionsFormatAbstractPubMedPMIDSharePermalinkCopyPagenavigationTitle&authorsAbstractSimilarartic
5. Approach to refractory gastroesophageal reflux disease in adults
Despite treatment with proton pump inhibitors (PPIs), some patients with ... ○H2 receptor antagonists – In patients with persistent acid reflux symptoms ... The combination did not increase healing of erosive esophagitis or ...
6. A Systematic Review and Meta-analysis of Randomized ...
Combination of prokinetics with PPI treatment is more effective than PPI alone in ... treatments, including histamine H2 receptor antagonists, prokinetics, alginate, ...HOMEAbouttheJournalArchivesForAuthorsForReviewersSubscriptionRequestPermissionTitleAuthorKeyword:::Volume:::Vol.27Vol.26Vol.25Vol.24Vol.23Vol.22Vol.21Vol.20Vol.19Vol.18Vol.17Vol.16Vol.15Vol.14Vol.13Vol.12Vol.11Vol.10Vol.9Vol.8Vol.7Vol.6Vol.5Vol.4Vol.3Vol.2Vol.1:::Issue:::No.4No.3No.2No.1Archives | Top10DOIsJNeurogastroenterolMotil2021;27(2):165-175 https://doi.org/10.5056/jnm20161ASystematicReviewandMeta-analysisofRandomizedControlTrials:CombinationTreatmentWithProtonPumpInhibitorPlusProkineticforGastroesophagealRefluxDiseaseDaHyunJung,1ChealWungHuh,2SangKilLee,1*JunChulPark,1SungKwanShin,1andYongChanLee11DepartmentofInternalMedicine,SeveranceHospital,YonseiUniversityCollegeofMedicine,Seoul,Korea;and2DepartmentofInternalMedicine,YonginSeveranceHospital,YonseiUniversityCollegeofMedicine,Seoul,KoreaCorrespondenceto:SangKilLee,MD,PhDDepartmentofInternalMedicine,YonseiUniversityCollegeofMedicine,50-1Yonsei-ro,Seodaemun-gu,Seoul03722,KoreaTel:+82-2-2228-1996,Fax:+82-2-393-6884,E-mail:sklee@yuhs.acDaHyunJungandChealWungHuhequallycontributedtothiswork.Received:July16,2020;Revised:December8,2020;Accepted:December28,2020;Publishedonline:April30,2021©TheKoreanSocietyofNeurogastroenterologyandMotility.Allrightsreserved.ThisisanOpenAccessarticledistributedunderthetermsoftheCreativeCommonsAttributionNon-CommercialLicense(http://creativecommons.org/licenses/by-nc/4.0)whichpermitsunrestrictednon-commercialuse,distribution,andreproductioninanymedium,providedtheoriginalworkisproperlycited.OtherSectionsAbstractIntroductionMethodsResultsDiscussionSupplementaryMaterialsFinancialsupportConflictsofinterestAuthorcontributionsReferencesAbstractBackground/AimsProkineticscanbeusedfortreatingpatientswithgastroesophagealrefluxdisease(GERD),whoexhibitsuboptimalresponsetoprotonpumpinhibitor(PPI)treatment.Weconductedasystematic
7. Combined use of proton pump inhibitors and histamine-H2 ...
Request PDF | Combined use of proton pump inhibitors and histamine-H2 receptor ... The proportion of patients who were heartburn-free was highest with PPIs ...HomeDigestiveSystemDiseasesGastrointestinalDiseasesStomachDiseasesInternalMedicineMedicineGastroenterologyGastroesophagealRefluxDiseaseArticleCombineduseofprotonpumpinhibitorsandhistamine-H2receptorantagonistsforGERDSeptember2002CanadianPharmaceuticalJournal135(7)Authors:DoretKFChengMountSinaiHospital,TorontoRequestfull-textPDFToreadthefull-textofthisresearch,youcanrequestacopydirectlyfromtheauthor.Requestfull-textDownloadcitationCopylinkLinkcopiedRequestfull-textDownloadcitationCopylinkLinkcopiedToreadthefull-textofthisresearch,youcanrequestacopydirectlyfromtheauthor.References(1)AbstractLifestylechangeshavenotbeenstudiedextensively;however,patientcounselingandimplementationofnon-pharma-cologicalmeasuresareintegraltothetreatmentofallstagesofGERD.H2RAswerehistoricallythemainstayoftherapyforGERD,particularlyforthesymptomatictreatmentofheartburn.Morerecently,PPIshaveassumedamoreprominentroleduetotheirpotentandlong-termsup-pressionofacidreleaseandsuperiorefficacyinhealingdocumentedesophagitis.2,3Ameta-analysisofrandom-izedcontrolledtrialsevaluatedthehealingratesandthedegreeofsymptomreliefprovidedbyH2RAsandPPIsinpatientswithGERDandmoderatetosevereesophagitis(GradeIItoIV).4TheoverallhealingproportionwasgreatestwithPPIs(83.6%)comparedwithH2RAs(51.9%),sucralfate(39.2%)orplacebo(28.2%).Theproportionofpatientswhowereheartburn-freewashighestwithPPIs(77.4%)comparedwithH2RAs(47.6%).Overall,PPIsshowedfasterhealingratesandmorecompleteheart-burnrelief.Thestudiesincludedinthismeta-analysiswererestrictedtothosethatassessedacutehealingofesophagitisratherthanmaintenancetherapyforrecur-rence.VariousPPIshavebeenapprovedinCanadafortheinitialtherapyofpatientswithmoresevereGERDsymptoms,thosewithendoscopicallydocumentedesophagitis,orthosewhohavenotrespondedtofourtoeightweeksofH2RAtherapy(Table1).NocturnalAcidBreakthroughDiscoverthewor
8. Long-term Effect of H2RA Therapy on Nocturnal Gastric Acid ...
onists (H2RAs) to proton pump inhibitor (PPI) therapy is a common ... Conclusions: The combination of H2RA and PPI therapy reduced NAB ... after 1 week of combination therapy. ... gastric acid with histamine-antagonist therapy is lacking.ThissiterequiresCookiestobeenabledtofunction.PleaseensureCookiesareturnedonandthenre-visitthedesiredpage.