FungizoneGenericName:amphotericinbBrandName:FungizoneLastupdatedonRxList:11/12/2020homedrugsa-zlistFungizone(AmphotericinB)sideeffectsdrugcenterRelatedDrugsImpavidoTolsuraFungizoneUserReviewsPROFESSIONALCONSUMERSIDEEFFECTSOverviewConsumerInformationProfessionalInformationFungizoneSideEffectsCenterFindLowestPricesonMedicalEditor:JohnP.Cunha,DO,FACOEPWhatIsFungizone?Fungizone(amphotericinB)isanantifungalantibioticusedtotreatserious,life-threateningfungalinfections,andisusuallygivenafterotherantifungalantibioticshavebeenunsuccessful.ThebrandnameFungizoneisdiscontinuedintheU.S.Genericformsmaybeavailable.WhatAreSideEffectsofFungizone?CommonsideeffectsofFungizone(amphotericinB)include:injectionsitereactions(pain,swelling,irritation),fever,shaking,chills,flushing,lossofappetite,weightloss,dizziness,nausea,vomiting,diarrhea,upsetstomach,headache,shortnessofbreath,muscleorjointaches,warmth/redness/tinglyfeelingunderyourskin,itchingorrash,orfastbreathing1to3hoursaftertheinfusionstarts.TellyourdoctorifyouhaveserioussideeffectsofFungizoneincluding:unusualtiredness,weakness,musclecramping,changesintheamountofurine,painfulurination,numbness/tinglingofarms/legs,visionchanges,hearingchanges(e.g.,ringingintheears),darkurine,severestomach/abdominalpain,yellowingeyes/skin,swellingankles/feet,fast/slow/irregularheartbeat,coldsweats,bluelips,easybruising/bleeding,othersignsofinfection(e.g.,fever,persistentsorethroat),mental/moodchanges,seizures,blackstools,orvomitthatlookslikecoffeegrounds.DosageforFungizoneDosageofamphotericinBisadjustedaccordingtothepatient'sclinicalstatus(e.g.,site,cause,andseverityofinfection,heartandkidneyfunction,etc.).Atestdoseisusuallydonetocheckforreaction,andtherapyisusuallyinitiatedwithadailydoseof0.25mg/kgofbodyweight,giveninaslowinfusionover2to6hours.WhatDrugs,Substances,orSupplementsInteractwithFungizone?AmphotericinBmayinteractwithflucytosine,digoxin,pentamidine,tacrolimus,musclerelaxers,steroids,antifungalantibiotics,antibiotics,antiviralmedicines,orcanc